MARC details
| 000 -LEADER |
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| fixed length control field |
04228cam a2200349 i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
18127938 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20220527075502.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
140425t20142014nyua b 001 0 eng |
| 010 ## - LIBRARY OF CONGRESS CONTROL NUMBER |
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| LC control number |
2014015021 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9781621820413 |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
DLC |
| Language of cataloging |
eng |
| Transcribing agency |
DLC |
| Description conventions |
rda |
| Modifying agency |
DLC |
| 042 ## - AUTHENTICATION CODE |
|---|
| Authentication code |
pcc |
| 050 00 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
QH323.5 |
| Item number |
.G565 2014 |
| 082 00 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
570.151 |
| Edition number |
22 |
| 084 ## - OTHER CLASSIFICATION NUMBER |
|---|
| Classification number |
SCI007000 |
| -- |
SCI072000 |
| -- |
SCI049000 |
| Number source |
bisacsh |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Glass, David J., |
| Relator term |
author. |
| 9 (RLIN) |
12371 |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Experimental design for biologists / |
| Statement of responsibility, etc. |
David J. Glass, Novartis Institutes for Biomedical Research. |
| 250 ## - EDITION STATEMENT |
|---|
| Edition statement |
Second edition. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
New York |
| Name of publisher, distributor, etc. |
Cold Spring Harbor |
| Date of publication, distribution, etc. |
2014 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
289 pages : |
| Dimensions |
26 cm |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc. note |
Includes bibliographical references and index. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Why you need to read a little philosophy first: the philosophy of science governs the practice of science -- Defining scientific research -- Why do science? What is science for? The need for inductive reasoning -- The first step to engaging in scientific research: establishing your framework -- A short history of philosophy relevant to scientific method: how we got to where we are today and the problem of induction -- The sky is red hypothesis: examining the hypothesis-falsification framework -- The hypothesis as a framework for scientific projects: is critical rationalism critical enough? -- Scientific settings in which a hypothesis-falsification framework is not feasible -- The question and the model: forming an inductive framework for scientific projects (by getting to Carnegie Hall) -- Advantages to the question/model-building inductive framework -- A biological example of the question/model-building framework -- Some concluding remarks on the philosophy of experimentation: warnings and exhortations -- The system -- System validation -- Choice of a model organism or technique: validation experiments -- System validation requirements for distinct experimental readouts -- System specificity: specificity of detection and specificity of perturbation -- System sensitivity: minimizing signal to noise to improve sensitivity of detection -- System stability -- Determining conditions to measure efficacy -- System validation: determining conditions to measure safety -- Definition of the experiment: the framework for an individual experiment -- The negative control: distinct types -- The requirement for the positive control -- Method and reagent controls -- Subject controls -- Assumption controls -- Experimentalist controls: establishing a claim to an objective perspective -- Biological replicates, technical replicates, experimental repeats, time courses (repeats over time), and dose responses -- Summary of the components of the individual experiment -- Building the model: representations of the experimental data -- Data filtration -- Model induction: asking follow-up questions and finishing the project by writing the manuscript -- A short synopsis -- Designing the experimental project: a biological example. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
"Experimental Design for Biologists is a unique and successful handbook on the theory and practice of effective design of scientific experiments, based on a well-received course by the author. This second edition is entirely reorganized, rewritten, and includes new material and figures. The material is presented in seven parts: Philosophy of Scientific Experimentation, Mapping Out the Project, System Validation, Experimental Design, Examples, What Comes After, and Putting It All Together. Experimental Design for Biologists, Second Edition, is an essential source in designing a sound research plan, critical to the success of graduate students"-- |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Biology |
| General subdivision |
Mathematical models. |
| 9 (RLIN) |
12372 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Experimental design. |
| 9 (RLIN) |
12373 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
SCIENCE / Life Sciences / Biochemistry. |
| Source of heading or term |
bisacsh |
| 9 (RLIN) |
12374 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
SCIENCE / Life Sciences / Biology / Developmental Biology. |
| Source of heading or term |
bisacsh |
| 9 (RLIN) |
12375 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
SCIENCE / Life Sciences / Biology / Molecular Biology. |
| Source of heading or term |
bisacsh |
| 9 (RLIN) |
12376 |
| 906 ## - LOCAL DATA ELEMENT F, LDF (RLIN) |
|---|
| a |
7 |
| b |
cbc |
| c |
orignew |
| d |
1 |
| e |
ecip |
| f |
20 |
| g |
y-gencatlg |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Books |