MARC details
000 -LEADER |
fixed length control field |
03897cam a22005537i 4500 |
001 - CONTROL NUMBER |
control field |
18352171 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
OSt |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20220527082425.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
141028s2015 nyua b 001 0 eng |
010 ## - LIBRARY OF CONGRESS CONTROL NUMBER |
LC control number |
2014955417 |
016 7# - NATIONAL BIBLIOGRAPHIC AGENCY CONTROL NUMBER |
Record control number |
101657482 |
Source |
DNLM |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9780231170840 |
Qualifying information |
(hardback) |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
023117084X |
Qualifying information |
(hardback) |
035 ## - SYSTEM CONTROL NUMBER |
System control number |
(OCoLC)ocn899332106 |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
NLM |
Language of cataloging |
eng |
Transcribing agency |
NLM |
Description conventions |
rda |
Modifying agency |
YDXCP |
-- |
BDX |
-- |
BTCTA |
-- |
ABG |
-- |
MNJ |
-- |
WKM |
-- |
VP@ |
-- |
SHH |
-- |
ZQP |
-- |
OCLCF |
-- |
GYG |
-- |
LMR |
-- |
OKJ |
-- |
DLC |
042 ## - AUTHENTICATION CODE |
Authentication code |
nlmcopyc |
-- |
lccopycat |
050 00 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
QP624 |
Item number |
.C368 2015 |
050 14 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
QH447 |
Item number |
.C37 2015 |
060 00 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER |
Classification number |
2015 D-954 |
060 10 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER |
Classification number |
QU 460 |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
572.86 |
Edition number |
22 |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Carey, Nessa, |
Relator term |
author. |
245 10 - TITLE STATEMENT |
Title |
Junk DNA : |
Remainder of title |
a journey through the dark matter of the genome / |
Statement of responsibility, etc. |
Nessa Carey. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
viii, 340 pages : |
Other physical details |
illustrations ; |
Dimensions |
24 cm |
504 ## - BIBLIOGRAPHY, ETC. NOTE |
Bibliography, etc. note |
Includes bibliographical references (pages 289-328) and index. |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
An introduction to genomic dark matter -- Why dark matter matters -- When dark matter turns very dark indeed -- Where did all the genes go? -- Outstaying an invitation -- Everything shrinks when we get old -- Two is the perfect number -- Painting with junk -- Playing the long game -- Adding colour to the dark matter -- Why parents love junk -- Junk with a mission -- Switching it on, turning it up -- No man's land -- Project ENCODE : Big Science comes to junk DNA -- Headless queens, strange cats and portly mice -- Lost in untranslation -- Why LEGO is better than Airfix -- Mini can be mighty -- The drugs do work (sometimes) -- Some light in the darkness -- Appendix. Human diseases in which junk DNA has been implicated. |
520 ## - SUMMARY, ETC. |
Summary, etc. |
For decades after the indentification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98 percent of the human genome were dismissed as "junk," sequences that serve no purpose. But researchers have recently discovered variations and modulations in this junk DNA that are involved with a number of intractable diseases. Our increasing knowledge of junk DNA has led to innovative research and treatment approaches that may finally ameliorate some of these conditions. Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. These functions have forced scientists to revisit the very meaning of the word "gene" and have endangered a spirited scientific battle over whether or not this genomic "nonsense" is the source of human biological complexity. Drawing on her experience with leading scientific investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, and evolution. We are only now unlocking the secrets of junk DNA, and Nessa Carey's book is an essential resource for navigating the history and controversies of this fast-growing, hotly disputed field. -- |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Genomics. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Human genome. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Eukaryotic cells. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Recombinant DNA. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Insertion elements, DNA. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Non-coding RNA. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Gene therapy. |
650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Genome, Human. |
650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
DNA. |
650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Genomics. |
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Eukaryotic cells. |
Source of heading or term |
fast |
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Gene therapy. |
Source of heading or term |
fast |
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Genomics. |
Source of heading or term |
fast |
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Human genome. |
Source of heading or term |
fast |
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Insertion elements, DNA. |
Source of heading or term |
fast |
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Non-coding RNA. |
Source of heading or term |
fast |
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Recombinant DNA. |
Source of heading or term |
fast |
906 ## - LOCAL DATA ELEMENT F, LDF (RLIN) |
a |
7 |
b |
cbc |
c |
copycat |
d |
2 |
e |
epcn |
f |
20 |
g |
y-gencatlg |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Books |