Pharmacogenomics: methods and protocols /
edited by Federico Inncocenti and Ron H.N van Schaik
- Second edition.
- New York Humana Press 2013
- xiii, 359 pages : illustrations (some colored) ; 25 cm.
- Methods in molecular biology, 1015 1064-3745 ; Springer protocols .
- Methods in molecular biology (Clifton, N.J.) ; 1015. Springer protocols (Series) .
Includes bibliographic references and index.
Pharmacogenomics : historical perspective and current status / Denaturing high-performance liquid chromatography for mutation detection and genotyping / Clinical SNP detection by the smartAmp method / MALDI-TOF mass spectrometry / TaqMan® drug metabolism genotyping assays for the detection of human polymorphisms involved in drug metabolism / Pyrosequencing of clinically relevant polymorphisms / Pharmacogenetics using Luminex® xMAP® technology : a method for developing a custom multiplex single nucleotide polymorphism mutation assay / Use of linkage analysis, genome-eide association studies, and next-generation sequencing in the identification of disease-causing mutations / GoldenGate genotyping assay : custom design, processing, and data analysis / Genome-wide gene expression profiling, genotyping, and copy number analyses of acute myeloid leukemia using affymetrix geneChips. / Epigenetic techniques in pharmacogenetics / Plasmid derived external quality controls for genetic testing / Allelic imbalance assays to quantify allele-specific gene expression and transcription factor binding / SCAN : a systems biology approach to pharmacogenomic discovery / Methods to examine the impact of nonsynonymous SNPs on protein degradation and function of human ABC transporter / In vitro identification of cytochrome P450 enzymes responsible for drug metabolism / In vitro and in vivo mouse models for pharmacogenetic studies / Hydrodynamic tail vein assay as a tool for the study of liver promoters and enhancers / Guide to the current web-based resources in pharmacogenomics / PharmGKB : the pharmacogenomics knowledge base / Genetic databases in pharmacogenomics : the frequency of inherited disorders database (FINDbase) / Development of predictive models for estimating warfarin maintenance dose based on genetic and clinical factors / Evidence based drug dosing and pharmacotherapeutic recommendations per genotype / Rosane Charlab and Lei Zhang -- Donna Lee Fackenthal ... [et al.] -- Toshihisa Ishikawa and Yoshihide Hayashizaki -- Dirk van den Boom, Matthias Wjst, and Robin E. Everts -- Toinette Hartshorne -- Cristi R. King and Sharon Marsh -- Gonnie Spierings and Sherry A. Dunbar -- Eric Londin ... [et al.] -- Anna González-Neira -- Mathijs A. Sanders and Peter J.M. Valk -- Sandra G. Heil -- Tahar van der Straaten and Henk-Jan Guchelaar -- Francesca Luca and Anna Di Rienzo -- Eric R. Gamazon, R. Stephanie Huang, and Nancy J. Cox -- Toshihisa Ishikawa, Kanako Wakabayashi-Nakao, and Hiroshi Nakagawa -- Zhengyin Yan and Gary W. Caldwell -- Amber Frick ... [et al.] -- Mee J. Kim and Nadav Ahituv -- Dylan M. Glubb ... [et al.] -- Caroline F. Thorn, Teri E. Klein, and Russ B. Altman -- Marianthi Georgitsi and George P. Patrinos -- Lu Yang and Mark W. Linder -- Vera H.M. Deneer and Ron H.N. van Schaik.