000			02645cam a2200457 i 4500
001			19018138
003			OSt
005			20220711075606.0
008			160316s2016 ne ac b 001 0 eng c
010			_a 2016936196
016	7		_a101695397 _2DNLM
020			_a9780128024010
035			_a(OCoLC)ocn898532986
040			_aNLM _beng _cNLM _erda _dBTCTA _dYDXCP _dBDX _dYDX _dVGM _dOCLCF _dOBE _dCRU _dOCLCO _dDLC
042			_apcc
050	0	0	_aQP363.2 _b.H83 2016
060	0	0	_a2016 I-198
060	1	0	_aWL 385
082	0	0	_a612.81046 _222
100	1		_aHubbard, Jacqueline A., _eauthor.
245	1	0	_aAstrocytes and epilepsy / _cJacqueline A. Hubbard and Devin K. Binder, Center for Glial-Neuronal Interactions, Division of Biomedical Sciences, School of Medicine, University of California, Riverside, CA, USA.
264		1	_aAmsterdam : _bElsevier/AP, Academic Press is an imprint of Elsevier _c[2016]
300			_axii, 381 pages : _billustrations (chiefly color), portraits ; _c25 cm
336			_atext _btxt _2rdacontent
337			_aunmediated _bn _2rdamedia
338			_avolume _bnc _2rdacarrier
500			_a"Elsevier science & technology books."
504			_aIncludes bibliographical references and index.
505	0		_aHistory of astrocytes -- Astrocytes in the mammalian brain -- Gliotransmitters -- Types of epilepsy -- Neuropathology of human epilepsy -- Astrocyte calcium signaling -- Potassium channels -- Water channels -- Glutamate metabolism -- Adenosine metabolism -- Gap junctions -- Blood-brain barrier disruption -- Inflammation -- Therapeutic targets and future directions.
520			_a"Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not freed of seizures by existing medications and become "medically refractory." Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects."-- _cPage 4 of cover.
650		0	_aAstrocytes.
650		0	_aEpilepsy _xMolecular aspects.
650	1	2	_aEpilepsy _xphysiopathology.
650	2	2	_aAstrocytes _xmetabolism.
650		7	_aAstrocytes. _2fast _0(OCoLC)fst00819380
700	1		_aBinder, Devin K., _eauthor.
906			_a7 _bcbc _cpccadap _d2 _eepcn _f20 _gy-gencatlg
942			_2ddc _cBK _n0
999			_c30458 _d30458