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|---|---|---|---|
| 001 | 18381898 | ||
| 003 | OSt | ||
| 005 | 20220527082418.0 | ||
| 008 | 141120s2015 enka b 001 0 eng d | ||
| 010 | _a 2014957585 | ||
| 020 | _a9780199688739 (hbk) | ||
| 020 | _a0199688737 (hbk) | ||
| 035 | _a(OCoLC)ocn909474054 | ||
| 040 |
_aYDXCP _beng _cYDXCP _dCDX _dEQO _dOCLCO _dABG _dILC _dDLC |
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| 042 | _alccopycat | ||
| 050 | 0 | 0 |
_aQH447 _b.P37 2015 |
| 082 | 0 | 4 |
_a572.86 _222 |
| 082 | 0 | 4 |
_a611.0181663 _222 |
| 100 | 1 |
_aParrington, John, _eauthor. |
|
| 245 | 1 | 4 |
_aThe deeper genome : _bwhy there is more to the human genome than meets the eye / _cJohn Parrington. |
| 250 | _aFirst edition. | ||
| 300 |
_av, 246 pages : _billustrations ; _c24 cm |
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| 504 | _aIncludes bibliographical references (pages 210-236) and indexes. | ||
| 505 | 0 | _aHow the genome lost its junk -- The inheritors -- Life as a code -- Switches and signals -- The spacious genome -- RNA out of the shadows -- It's a jungle in there! -- The genome in 3D -- The jumping genes -- The marks of Lamarck -- Code, non-code, garbage, and junk -- Genes and disease -- What makes us human? -- The genome that became conscious -- The case for complexity. | |
| 520 | _aAs the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way... but the emerging picture is if anything far more exciting. Parrington gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact of its 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes of Neanderthals as well as that of chimps about the development of our species.-- | ||
| 650 | 0 | _aHuman genome. | |
| 650 | 0 |
_aGenomes. _919906 |
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| 650 | 0 | _aDNA. | |
| 856 | 4 | 2 |
_3Contributor biographical information _uhttp://www.loc.gov/catdir/enhancements/fy1512/2014957585-b.html |
| 856 | 4 | 2 |
_3Publisher description _uhttp://www.loc.gov/catdir/enhancements/fy1512/2014957585-d.html |
| 856 | 4 | 1 |
_3Table of contents only _uhttp://www.loc.gov/catdir/enhancements/fy1512/2014957585-t.html |
| 906 |
_a7 _bcbc _ccopycat _d2 _encip _f20 _gy-gencatlg |
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| 942 |
_2ddc _cBK |
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| 999 |
_c6988 _d6988 |
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